Some players need multiple channels or modes and lots of controls. Others want simplicity. For some, it's all about great clean tones, and for others, it's all about high gain tones. Some need a great reverb, others hate reverb on an amp. Then there are those who need to replicate a ton of sounds and go digital.
I just go for a great-sounding amp, and am less concerned about channel-switching and modes because I use my guitar's volume controls for that. Though I go back to the days of only single-channel amps being available, I've had a bunch of channel switchers, and basically, if it sounds good, I can make it work regardless.
Sooo....What's your bag?