I've had several SEs and been through my share of production model MD made PRSi and the quality on both, as compared to competitors, is superior. You can't go wrong with either. Boogie is right, as soon as I got my first PRS, an SE Singlecut, I was looking to buy another. Next one was a MD made CE22 and I've never looked back. Every PRSi I have had has been flawless, tone is subjective to some extent and not every PRS works for every player or type of music. That said, I can't say the same for Gibson for example. It took me awhile to find an LP that just felt 'right' and had the type of build quality I expect from an instrument in that price range.